Whole cigarettes (3 cigarettes from 3 different packages of the same variety) were extracted and analyzed in triplicate for the major commercial sensory cooling agents (menthol, WS-3, WS-23, WS-12, Frescolat MGA, Frescolat ML, Frescolat X-cool) by gas chromatography - mass spectrometry following published protocols (Supplementary file) 3
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As the FDA works to design and implement regulations that will reduce the addictiveness and potential harms associated with combustible cigarette smoking, attention has shifted towards the role of a new tobacco product, generally referred to as an electronic cigarette (e-cigarette)